The U.S.A., as represented by the Secretary, Department of Health and Human Services;Lentigen Technology, Inc.
发明人:
Rimas Orentas,Dina Schneider,Boro Dropulic,Dimiter S. Dimitrov,Zhongyu Zhu
申请号:
US16588357
公开号:
US20200101109A1
申请日:
2019.09.30
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Chimeric antigen receptors containing CD33 antigen binding domains are disclosed. Nucleic acids, recombinant expression vectors, host cells, antigen binding fragments, and pharmaceutical compositions, relating to the chimeric antigen receptors are also disclosed. Methods of treating or preventing cancer in a subject, and methods of making chimeric antigen receptor T cells are also disclosed.