Compositions comprising NDGA derivatives and sorafenib and their use in the treatment of cancer

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专利权人:

ザ・ジョンズ・ホプキンス・ユニバーシティ

发明人:

デービッド モルド,ルー チー ホワーン,クリストファー ルーランド,リヤーン ユイ－チュワン,ジョン ホ チュン,リヤーン ユイ-チュワン

申请号：

JP2014555812

公开号：

JP6205373B2

申请日:

2013.02.04

申请国别(地区):

JP

年份:

2017

代理人:

摘要：

The present invention provides pharmaceutical compositions comprising derivatives of NDGA, including M4N (tetra-O-methyl nordihydroguaiaretic acid) and sorafenib and their use in the inhibition and treatment of neoplastic diseases, such as liver cancer, colon cancer, breast cancer, brain cancers and ovarian cancers, for example, in a subject. Compositions comprising derivatives of NDGA, including M4N, sorafenib and additional therapeutic agents are also provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/