Ru Chih Huang,David Mold,Christopher Ruland,Yu-Chuan Liang,Jong Ho Chun
申请号:
US14374323
公开号:
US09877978B2
申请日:
2013.02.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides pharmaceutical compositions comprising derivatives of NDGA, including M4N (tetra-O-methyl nordihydroguaiaretic acid) and sorafenib and their use in the inhibition and treatment of neoplastic diseases, such as liver cancer, colon cancer, breast cancer, brain cancers and ovarian cancers, for example, in a subject. Compositions comprising derivatives of NDGA, including M4N, sorafenib and additional therapeutic agents are also provided.