Christopher Ruland;David Mold;Yu-Chuan Liang;Ru Huang;The Johns Hopkins University;Jong Chun
发明人:
Huang, Ru Chih,Mold, David,Ruland, Christopher,Liang, Yu-Chuan,Chun, Jong Ho
申请号:
AU2013214731
公开号:
AU2013214731B2
申请日:
2013.02.04
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The present invention provides pharmaceutical compositions comprising derivatives of NDGA, including M4N (tetra-O-methyl nordihydroguaiaretic acid) and sorafenib and their use in the inhibition and treatment of neoplastic diseases, such as liver cancer, colon cancer, breast cancer, brain cancers and ovarian cancers, for example, in a subject. Compositions comprising derivatives of NDGA, including M4N, sorafenib and additional therapeutic agents are also provided.