To provide a therapeutic method that increases the medicinal effects of taxane-based anti-tumor agents on various tumors. As a review result of methods for enhancing the anti-tumor effects of taxane-based anti-tumor agents, the inventors have completed the present invention by confirming that a composition or a salt thereof as an active ingredient for the treatment of cancer, said composition containing N2-(2E)-3-(4-chlorophenyl)-2-[acryloyl acyl]-N[2-carbonyl-2-(4-{[6-(trifluoromethyl)pyrimidin-4-yl] oxygen} piperidin-1-yl)ethyl]-3-pyridin-2-yl-L-propylamine amide (FK330), can enhance the anti-tumor effects of taxane-based anti-tumor agents. Namely, the present invention relates to a composition for the treatment of cancer, which contains FK330 or a salt thereof as an active ingredient, and which is for pharmaceutical dosage in combination with one or more anti-tumor agents that are selected from taxane-based anti-tumor agents.本發明之課題係尋求增大紫杉烷系抗腫瘤劑對各種腫瘤之藥效之治療方法。本發明之解決手段係本發明者對於增強紫杉烷系抗腫瘤劑之抗腫瘤作用之方法,進行檢討之結果,確認含有N2-〔(2E)-3-(4-氯苯基)-2-丙烯醯基〕-N-〔2-羰基-2-(4-{〔6-(三氟甲基)嘧啶-4-基〕氧}哌啶-1-基)乙基〕-3-吡啶-2-基-L-丙胺醯胺(FK330)或其鹽作為有效成份之癌治療用組成物,增強紫杉烷系抗腫瘤劑之抗腫瘤作用,完成本發明。亦即,本申請書係關於與選自紫杉烷系抗腫瘤劑中1種以上之抗腫瘤劑之並用投與用之含有FK330或其鹽作為有效成份之癌治療用組成物,作為某種型態係前列腺癌或卵巢癌治療用組成物。
