針對前蛋白轉化酶枯草桿菌蛋白酶加工酶9型之抗原結合蛋白农业专利-农业专业知识服务系统

发明人:: JACKSON, SIMON MARK,杰克森　赛门　马克,傑克森　賽門　馬克,WALKER, NIGEL PELHAM CLINTON,沃克　奈吉尔　佩尔汉　柯林顿,沃克　奈吉爾　佩爾漢　柯林頓,PIPER, DEREK EVAN,派普尔　德里克　艾凡,派普爾　德里克　艾凡,SHAN, BEI,单倍,單倍,SHEN, WENYAN,沈文彦,沈文彥,CHAN, JOYCE CHI YEE,陈志怡

摘要：: Antigen binding proteins that interact with Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) are described. Methods of treating hypercholesterolemia and other disorders by administering a pharmaceutically effective amount of an antigen binding protein to PCSK9 are described. Methods of detecting the amount of PCSK9 in a sample using an antigen binding protein to PCSK9 are described.本發明描述與前蛋白轉化酶枯草桿菌蛋白酶加工酶9型(PCSK9)相互作用之抗原結合蛋白。本發明描述藉由投與醫藥學上有效量的針對PCSK9之抗原結合蛋白以治療高膽固醇血症及其他病症的方法。本發明描述使用針對PCSK9之抗原結合蛋白偵測樣品中之PCSK9之量的方法。