KVISTGAARD, ANNE STAUDT,WEJSE, PETER LANGBORG,DONOVAN, SHARON,SIEGEL, MARCIA H. MONACO,COMSTOCK, SARAH S.
申请号：
PL14735964
公开号：
PL3016673T3
申请日:
2014.07.04
申请国别(地区):
PL
年份:
2018
代理人:
摘要：
The disclosed invention provides mammalian milk osteopontin and/or an active truncation or active peptide thereof for improving immune responsiveness to an infectious disease in a mammal, for example a human subject, as well as enhancing the efficacy of vaccination for the prophylactic or therapeutic treatment of an infectious disease in mammals, such as humans. The invention further provides a vaccine system, for use in the prophylactic or therapeutic treatment of an infectious disease in a mammal, comprising a vaccine and a mammalian milk osteopontin and/or an active truncation or active peptide thereof for oral administration to a mammal, as well as methods of enhancing immune resistance to an infectious disease in a mammal by administration of a vaccine and a mammalian milk osteopontin and/or an active truncation thereof.
