KVISTGAARD, Anne Staudt,WEJSE, Peter Langborg,DONOVAN, Sharon,SIEGEL, Marcia H. Monaco,COMSTOCK, Sarah S
申请号：
PH12015502844
公开号：
PH12015502844B1
申请日:
2015.12.21
申请国别(地区):
PH
年份:
2016
代理人:
摘要：
The disclosed invention provides mammalian milk osteopontin and/or an active truncation or active peptide thereof for improving immune responsiveness to an infectious disease in a mammal, for example a human subject, as well as enhancing the efficacy of vaccination for the prophylactic or therapeutic treatment of an infectious disease in mammals, such as humans. The invention further provides a vaccine system, for use in the prophylactic or therapeutic treatment of an infectious disease in a mammal, comprising a vaccine and a mammalian milk osteopontin and/or an active truncation or active peptide thereof for oral administration to a mammal, as well as methods of enhancing immune resistance to an infectious disease in a mammal by administration of a vaccine and a mammalian milk osteopontin and/or an active truncation thereof.
