Anne Staudt Kvistgaard,Peter Langborg Wejse,Sharon Donovan,Marcia H. Monaco Siegel,Sarah S. Comstock
申请号：
US15945517
公开号：
US20180289798A1
申请日:
2018.04.04
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The disclosed invention provides mammalian milk osteopontin and/or an active truncation or active peptide thereof for improving immune responsiveness to an infectious disease in a mammal, for example a human subject, as well as enhancing the efficacy of vaccination for the prophylactic or therapeutic treatment of an infectious disease in mammals, such as humans. The invention further provides a vaccine system, for use in the prophylactic or therapeutic treatment of an infectious disease in a mammal, comprising a vaccine and a mammalian milk osteopontin and/or an active truncation or active peptide thereof for oral administration to a mammal, as well as methods of enhancing immune resistance to an infectious disease in a mammal by administration of a vaccine and a mammalian milk osteopontin and/or an active truncation thereof.
