Angus Zoen Lau,Albert Po-Fu Chen,Charles H. Cunningham
申请号:
US13841945
公开号:
US09283317B2
申请日:
2013.03.15
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Disclosed embodiments for assessing brown adipose tissue use imaging of metabolic contrast agents. For example, activated brown adipose tissue may be assessed by evaluating a difference in production of the hyperpolarized 13C metabolic contrast agent from a pre-polarized 13C metabolic contrast agent precursor before and after exposure of the subject to an activating event or agent. In one embodiment, the subject is given a dose of norepinephrine, and the production of the hyperpolarized 13C metabolic contrast agent before and after the dose is assessed.