The present invention relates to a pharmaceutical composition comprising an oxazine derivative BACE-1 inhibitor, a process for the preparation thereof, and its use in the treatment or prevention of Alzheimer’s disease.本發明係關於包含㗁?衍生物BACE-1抑制劑之醫藥組合物、其製備方法,及其治療或預防阿茲海默症(Alzheimer’s disease)之用途。