Systems, methods, and apparatus for processing cell therapy products are provided. A closed system can include a container, an expandable seal, a connector, and a needle for aspirating. The container can have an interior configured to hold at least one cellular therapy product. The expandable seal can be coupled to the container and form a barrier between an external environment and the interior of the container. The connector can be coupled to the expandable seal. The needle can be operatively coupled to the connector, and a distal end of the needle can extend from the connector into the interior of the container. The position of the distal end of the needle can be selectively adjusted between a first depth in the interior of the container and a second depth in the interior of the container without exposing the needle to the external environment.
