Provided is a vascular prosthesis that has various properties required of it and is highly effective in promoting the settlement of adherent vascular endothelial cells. In particular, provided is a vascular prosthesis with tubular woven structure, the prosthesis comprising an inner layer to be in contact with a blood flow, the inner layer being formed of warp and weft yarns and having a cover factor of 1800 or more, each of the warp and weft yarns comprising a microfiber multifilament yarn with a monofilament fineness of 0.50 dtex or less, the multifilament yarn comprising microfiber monofilaments having an average intersecting angle S of the monofilaments of less than 25°.提供具備人工血管所被冀求的諸特性的同時,血管內皮細胞固著性優異的人工血管。一種筒狀織物構造之人工血管,其中構成與血流接觸的內層的經紗及緯紗之各者係包含微纖維複絲,其係單紗纖度0.50dtex以下之微纖維複絲,各微纖維單紗彼此交叉,前述交叉平均角度設為S時,S<25°,且織物覆蓋係數係1800以上。