Provided is a vascular prosthesis endowed with the properties required of a vascular prosthesis together with an excellent vascular endothelial cell fixing property. A vascular prosthesis of a tubular fabric structure containing microfiber multifilaments in which each warp and weft constituting the inner layer in contact with the blood flow has a monofilament fineness of 0.50 dtex or less, each microfiber monofilament intersects another, S < 25° when the average angle of intersection is taken to be S, and the cover factor is 1800 or higher.
