method of treating muscle injury, muscle loss, muscle degeneration, muscle atrophy or reduced rate of muscle repair; pharmaceutical composition; compound use in the manufacture of a medicament for the treatment of muscle injury, muscle loss, muscle degeneration, muscle atrophy or reduced rate of muscle repair
METHOD OF TREATMENT OF MUSCULAR INJURY, MUSCLE LOSS, MUSCLE DEGENERATION, MUSCULAR ATROPHY OR REDUCED MUSCULAR REPAIR RATE; PHARMACEUTICAL COMPOSITION; AND USE OF COMPOUND IN THE MANUFACTURE OF A MEDICINAL PRODUCT FOR TREATMENT OF MUSCULAR INJURY, MUSCLE LOSS, MUSCULAR ATROPHY OR REDUCED MUSCLE REPAIR RATE. This invention describes novel methods of treating muscle injury, muscle loss, muscle degeneration, muscle atrophy, or reduced rates of muscle repair associated with various conditions, such as muscle dystrophy, by using small molecule PAI-1 inhibitors.MéTODO DE TRATAMENTO DE LESãO MUSCULAR, PERDA MUSCULAR, DEGENERAçãO MUSCULAR, ATROFIA MUSCULAR OU TAXA REDUZIDA DE REPARO MUSCULAR; COMPOSIçãO FARMACêUTICA; E USO DE COMPOSTO NA FABRICAçãO DE UM MEDICAMENTO PARA O TRATAMENTO DE LESãO MUSCULAR, PERDA MUSCULAR, DEGENERAçãO MUSCULAR, ATROFIA MUSCULAR OU TAXA REDUZIDA DE REPARO MUSCULAR. Esta invenção descreve novos métodos de tratamento de lesão muscular, perda muscular, degeneração muscular, atrofia muscular ou taxas reduzidas de reparo muscular associadas a várias condições, como distrofia muscular, mediante uso de inibidores de PAI-1 de pequena molécula.