DURRANT, LINDA GILLIAN,BRENTVILLE, VICTORIA ANNE,METHERINGHAM, RACHEL LOUISE
申请号：
CA2874515
公开号：
CA2874515A1
申请日:
2013.08.07
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
Anti-tumour immune responses to modified self-epitopes The present invention relates to the use of tumour-associated epitopes in medicine and in particular in the treatment of cancer. The epitopes stimulate an immune reaction against the tumour and have a modification selected from deimination of arginine to citrulline, nitration of tyrosine, oxidation of tryptophan and deamination of glutamine or asparagine. The invention also relates to nucleic acids comprising sequences that encode such epitopes for use in the treatment of cancer.
