DURRANT LINDA GILLIAN,BRENTVILLE VICTORIA ANNE,METHERINGHAM RACHEL LOUISE
申请号：
IN10629DEN2014
公开号：
IN10629DEN2014A
申请日:
2014.12.12
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
Anti tumour immune responses to modified self epitopes The present invention relates to the use of tumour associated epitopes in medicine and in particular in the treatment of cancer. The epitopes stimulate an immune reaction against the tumour and have a modification selected from deimination of arginine to citrulline nitration of tyrosine oxidation of tryptophan and deamination of glutamine or asparagine. The invention also relates to nucleic acids comprising sequences that encode such epitopes for use in the treatment of cancer.
