您的位置: 首页 > 农业专利 > 详情页

Recognition molecules for treatment and detection of tumours
专利权人:
GLYCOTOPE GMBH
发明人:
GOLETZ STEFFEN,Goletz Steffen,DANIELCZYK ANTJE,Danielczyk Antje,STAHN RENATE,Stahn Renate,KARSTEN UWE,Karsten Uwe
申请号:
SI200432082
公开号:
SI2053063T1
申请日:
2004.01.23
申请国别(地区):
SI
年份:
2013
代理人:
摘要:
Recognition molecules (I) comprising sequences that bind specifically to the glycosylated MUC1 tumor epitope, are new. New recognition molecules (I) comprise: (a) sequences (1) or (2) (b) sequences (3) or (4) and (c) sequences (5) and (6), and bind specifically to the glycosylated MUC1 tumor epitope. Asp-Ala-Trp-Met-Asp (1) Asn-Tyr-Trp-Met-Asn (2) Glu-Ile-Arg-Ser-Lys-Ala-Asn-Asn-His-Ala-Thr-Tyr-Tyr-Ala-Glu-Ser-Val-Lys-Gly (3) Glu-Ile-Arg-Leu-Lys-Ser-Asn-Asn-Tyr-Thr-Thr-His-Tyr-Ala-Glu-Ser-Val-Lys-Gly (4) Gly-Gly-Tyr-Gly-Phe-Asp-Tyr (5) His-Tyr-Tyr-Phe-Asp-Tyr (6) Independent claims are also included for the following: (1) construct (II) comprising (I) fused, chemically coupled or non-covalently associated with additional sequences and/or structures (2) isolated nucleic acid (III) that encodes (I) or (II) (3) expression cassette or vector that contains (III), operatively linked to a promoter (4) virus or host cell comprising at least one cassette or vector of (3) (5) organism containing at least one host cell of (4) (6) method for preparing (I) and (II) and (7) kit containing (I) and/or (II). ACTIVITY : Cytostatic. No details of tests for cytostatic activity are given. MECHANISM OF ACTION : Specific binding to the MUC1 epitope Gene therapy.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

意 见 箱

匿名:登录

个人用户登录

找回密码

第三方账号登录

忘记密码

个人用户注册

必须为有效邮箱
6~16位数字与字母组合
6~16位数字与字母组合
请输入正确的手机号码

信息补充