MOORE STEPHEN JAMES,NGUYEN MARGARET THY LUU,HOSTETTER DANIEL R,VASILJEVA OLGA
申请号：
IN201627027704
公开号：
IN201627027704A
申请日:
2016.08.12
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
The invention relates generally to polypeptides that include a cleavable moiety that is a substrate for at least one protease selected from matriptase and u plasminogen activator (uPA) to activatable antibodies and other larger molecules that include the cleavable moiety that is a substrate for at least one protease selected from matriptase and u plasminogen activator and to methods of making and using these polypeptides that include a cleavable moiety that is a substrate for at least one protease selected from matriptase and uplasminogen activator in a variety of therapeutic diagnostic and prophylactic indications.
