CRAWFORD, James John,ORTWINE, Daniel Fred,WEI, BinQing,YOUNG, Wendy B.
申请号：
AU2018201557
公开号：
AU2018201557A1
申请日:
2018.03.05
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
#$%^&*AU2018201557A120180322.pdf#####ABSTRACT Heteroaryl pyridone and aza-pyridone compounds of Formula I are provided, where one or two of X1, X2, and X 3 are N, and including stereoisomers, tautomers, and 5 pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. R 5 N H R4 Y 2 0 R1 N, R6 X1 -x 3 X 2 10
