CRAWFORD, James John,ORTWINE, Daniel Fred,WEI, BinQing,YOUNG, Wendy B.
申请号：
AU2020202707
公开号：
AU2020202707A1
申请日:
2020.04.22
申请国别(地区):
AU
年份:
2020
代理人:
摘要：
#$%^&*AU2020202707A120200514.pdf#####ABSTRACT Heteroaryl pyridone and aza-pyridone compounds of Formula I are provided, where one or two of X, X2, and X3 are N, and including stereoisomers, tautomers, and 5 pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed. R5 NH R4 y2 O RN N RT Y1 R6 X 1 x3 X2' 0
