A biomedical device including an energy source, an electro-active device operatively connected to the energy source, circuitry configured to control operation of the electro-active device, at least one barrier layer including at least one inorganic material surrounding the energy source, electro-active device and circuitry, and at least one molded layer surrounding the at least one barrier layer. A method for encapsulating electronic components of an electro-active biomedical device in a protective envelope containing a barrier layer including at least one inorganic compound, and a molded polymer overcoat.