FORMES CRISTALLINES DE 4- (2- ((1R,2R)-2-HYDROXYCYCLOHEXYLAMINO) BENZOTHIAZOL-6-YLOXY)-N-METHYLPICOLINAMIDE

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专利权人:

NOVARTIS AG

发明人:

GRANDEURY, ARNAUD,WAYKOLE, LILADHAR MURLIDHAR

申请号：

CA3039764

公开号：

CA3039764A1

申请日:

2017.10.13

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

This application relates to various crystalline forms of 4-(2-((1R,2R)-2-hydroxycyclohexylamino)benzothiazol-6-yloxy)-N-methylpicolinamide hydrochloride salts as well as compositions and methods of using the same. In some embodiments the crystalline forms also contain water ("hydrates"). These materials are useful in the treatment of various diseases, including glioblastoma multiforme, breast cancer, pancreatic cancer and other solid tumors.

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