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CRYSTALLINE FORMS OF 4-(2-((1R,2R)-2-HYDROXYCYCLOHEXYLAMINO)BENZOTHIAZOL-6-YLOXY)-N-METHYLPICOLINAMIDE
专利权人:
Novartis AG
发明人:
Arnaud GRANDEURY,Liladhar Murlidhar WAYKOLE
申请号:
US16341124
公开号:
US20200190057A1
申请日:
2017.10.13
申请国别(地区):
US
年份:
2020
代理人:
摘要:
This application relates to various crystalline forms of 4-(2-((1R,2R)-2-hydroxycyclohexylamino)benzothiazol-6-yloxy)-N-methylpicolinamide hydrochloride salts as well as compositions and methods of using the same. In some embodiments the crystalline forms also contain water (“hydrates”). These materials are useful in the treatment of various diseases, including glioblastoma multiforme, breast cancer, pancreatic cancer and other solid tumors.
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