Wang Mao;Anthony S. Prokopowicz, III;Tina Marie Morwick
发明人:
Wang Mao,Tina Marie Morwick,Anthony S. Prokopowicz, III
申请号：
US12377283
公开号：
US08318723B2
申请日:
2007.08.15
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The invention provides compounds according to formula (I)their use and methods for preparation wherein A, X, Y, R1, R2 and R3 are defined herein. The compounds of the invention inhibit specific serine/threonine kinases involved in inflammatory processes and aberrant cell proliferation, and are thus useful for treating associated diseases and pathological conditions such as Pim kinase-mediated diseases and pathological conditions involving inflammation, including Chron's disease, inflammatory bowel disease, rheumatoid arthritis, and chronic inflammatory disease, or aberrant cell proliferation including various cancers.
