Pyrazine compounds, their use and methods of preparation

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专利权人:

ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング

发明人:

モーウィック ティナ マリー,プロコポウィッツ アンソニー エス,マオ ワン

申请号：

JP2009524774

公开号：

JP5252404B2

申请日:

2007.08.15

申请国别(地区):

JP

年份:

2013

代理人:

摘要：

The invention provides compounds according to formula (I) their use and methods for preparation wherein A, X, Y, R1, R2 and R3 are defined herein. The compounds of the invention inhibit specific serine/threonine kinases involved in inflammatory processes and aberrant cell proliferation, and are thus useful for treating associated diseases and pathological conditions such as Pim kinase-mediated diseases and pathological conditions involving inflammation, including Chron's disease, inflammatory bowel disease, rheumatoid arthritis, and chronic inflammatory disease, or aberrant cell proliferation including various cancers.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/