Martin James Inglis Andrews;Grégory Louis Joseph Bar;Mark Stuart Chambers;Wolfgang Schmidt
发明人:
Martin James Inglis Andrews,Mark Stuart Chambers,Wolfgang Schmidt,Grégory Louis Joseph Bar
申请号:
US12753383
公开号:
US08138193B2
申请日:
2010.04.02
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Novel fused pyrazine compounds are disclosed that have a formula represented by the following:with Z, R1, R2, R8 and R9 as defined in the written description. The compounds may be prepared as pharmaceutical compositions, and may be used for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammation, rheumatoid arthritis and others.