Useful for treating Diseases caused by a dysregulated protein kinase activity, such as cancer. It also provides methods for preparing such Compounds, Pharmaceutical compositions comprising these Compounds, and Methods for treating Diseases using these compounds or the pharmaceutical compositions containing them.Claim 1: a compound characterized by the formula (1), where ar is a group selected from the compounds of formula (AR1, ar2) or (AR3), where R1 is nr6r7 0R8 sonr9,,,, cor10, Nitro, cyano group or an optionally substituted cycloalkyl selected between C3 - 6, and Rociclilo and heteroaryl； R2, R3, R4 and R5 are independently Hydrogen, halogen, Nitro, cyano,Sonr9, cor10, nr11r12 OR13 or optionally replaced, a group selected from straight or branched alkyl - 6 C1, C2 alquenilo straight or branched - 6, 6 - straight or branched alquinilo C2, C3 and heterociclilo cycloalkyl - 6, where a is a C1 - 6 straight or branched alkyl substituted with a Group. Held between a heterociclilo optionally substituted, optionally substituted heteroaryl,Sonr9, cor10, and nr11r12 OR13； R6 is Hydrogen or optionally substituted alkyl group selected from straight or branched C1 - 6 - 6, alquenilo C2 straight or branched, alquinilo C2 - C3 - 6 straight or branched, 6 heterociclilo, cycloalkyl, aryl and heteroaryl； R7 is Hydrogen, sonr9, cor10,A C1 - 6 straight or branched alkyl group or an optionally substituted replaced selected from straight or branched alquenilo C2 - 6, 6 - straight or branched alquinilo C2, C3 - 6 heterociclilo cycloalkyl, aryl or heteroaryl, and R6 and R7, taken together with the nitrogen Atom to which they are attached S, Can form a group heterociclilo R8 is Hydrogen, optionally substituted；,Cor10 or optionally substituted Group selected from straight or branched alquenilo C2 - 6, 6 - straight or branched alquinilo C2, C3 - 6 heterociclilo, cycloalkyl, aryl and heteroaryl, where is as defined above； or nr11r12 R9 is selected among a group optionally substituted alq U
