YASRI, ABDELAZIZ,CHEVE, GWÉNAËL,BORIES, CÉDRIC,DELON, LOUIS
申请号：
ES10710439
公开号：
ES2540962T3
申请日:
2010.02.12
申请国别(地区):
ES
年份:
2015
代理人:
摘要：
Compounds of general formula I: ** Formula ** in which R represents: - an NHCOR1 group, or - an NR3R4 group in which R1 represents: - an aryl group optionally mono- or polysubstituted with: - a halogen atom, - a nitro group, - a cyano group, - a methylthiazyl group, - an alkoxy group, - a trifluoroalkoxy group, - an aryloxy group, - a trifluoroalkyl group, - a substituted or unsubstituted sulfonamide group, - a heteroaryl, optionally mono - or polysubstituted with a halogen atom, - a linear or branched C1-C6 alkyl group, - or a group selected from groups A, B, C, D or E as defined below: ** Formula ** - a heteroaryl group, - a cycloalkyl group, - a linear or branched C1-C6 alkyl group, or - a C1-C6 aralkyl group, optionally mono- or polysubstituted with an alkoxy group, 10 and / or a halogen atom , R2 represents: - a COOR14 ester group, - an alkyl group CH2R9, CH2OCOR10, CH2NR11R12, - an amide group CONR7R8, or - a COR13, R7 and R8 group, which may be identical or different, represent: - a hydrogen atom, - a C1-C6 aminoalkyl group, or - a C1-C6 morpholinoalkyl group, R9 represents: - a group heteroaryl, - a heterocyclic group, - an alkoxy group, or - a hydroxyl group, R10 represents: - a heteroaryl group, R11 and R12, which can be identical or different, represent: - a hydrogen atom, - an alkyl group of Linear or branched C1-C6, - an aralkyl group, - a C1-C6 alkoxyalkyl group, - a cycloalkyl group, optionally mono- or polysubstituted with a C1-C6 alkyl group, - an aryl group, optionally mono- or polysubstituted with:Compuestos de fórmula general I:**Fórmula** en la que R representa: - un grupo NHCOR1, o - un grupo NR3R4 en los que R1 representa: - un grupo arilo opcionalmente mono- o polisustituido con: - un átomo de halógeno, - un grupo nitro, - un grupo ciano, - un grupo metiltiazilo, - un grupo alcoxi, - un grupo trifluoroalcoxi, - un grupo ariloxi, - un grupo trifluoroalquilo, - un grupo sulfonamida sustituido o no sustituido, - un heteroarilo, opcionalmente mon
