This Hair is bright to be provided by leading to the miaow azoles and oxazine compounds or its Which that formula (I) indicates,It can be used as Biao Now go out AKT inhibit effect Should Kang Swollen tumor Elixirs [in The general formula,A,B,C and D Fen Do indicate N atom or C-R1a,N atom or C-R1b,N atom or C-R1c,And N atom or C-R1d； R1a,R1b,R1c and R1d are identical or different,And and respectively expression Hydrogen atom,Halogen atom,Cyano,6 alkyl of C1 of Ren Election substitution,6 alkoxy of C1 of Ren Election substitution,The not Eat He Miscellaneous Ring base that the carbonyl or Ren Election that Ren Election replaces replace； R2 indicates the not Eat He Miscellaneous Ring base that the aryl Huo Ren Election that Ren Election replaces replaces； And R3 and R4 is identical or different,And and indicate Hydrogen atom,Hydroxyalkyl base,The 7 Ring alkyl of C3 that the 6 alkyl Huo Ren Election of C1 that Ren Election replaces replaces].本發明提供了由通式(I)表示的咪唑并噁嗪化合物或其鹽，其可用作表現出AKT抑制效應的抗腫瘤劑[在該通式中，A、B、C和D分別表示N原子或C-R1a、N原子或C-R1b、N原子或C-R1c，以及N原子或C-R1d；R1a、R1b、R1c和R1d相同或不同，並且各自表示氫原子、鹵原子、氰基、任選取代的C1 6烷基、任選取代的C1 6烷氧基、任選取代的羰基或者任選取代的不飽和雜環基；R2表示任選取代的芳基或任選取代的不飽和雜環基；以及R3和R4相同或不同，並且表示氫原子、羥基、任選取代的C1 6烷基或任選取代的C3 7環烷基]。
