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Urea-substituted aromatic ring-linked dioxane-quinazoline and -linked dioxane-quinoline compounds, preparation method therefor and use thereof
专利权人:
Beijing Scitech-MQ Pharmaceuticals Limited
发明人:
Zhang, Qiang,Zhang, Hongbo,Yang, Leifu,Yang, Hailong,Zhou, Likai,Zheng, Nanqiao,Yu, Shannan,Wang, Zhongxiang,Feng, Shouye,Xu, Zhanqiang
申请号:
AU2018226922
公开号:
AU2018226922A1
申请日:
2018.02.11
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The present invention relates to a urea-substituted aromatic ring-linked dioxane-quinazoline compound of formula (1) and a urea-substituted aromatic ring-linked dioxane-quinoline, or a pharmaceutically acceptable salt thereof or a hydrate thereof. Also provided are the preparation of the compound as shown in formula (1) and the pharmaceutically acceptable salt thereof and the use thereof as a drug. The drug is used as an inhibitor of tyrosine kinases (e.g., VEGFR-2, C-RAF, B-RAF) for treating tyrosine kinase-related diseases.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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