The present invention relates to a medical dermatological preparation for external use comprising an active drug, polyoxyethylene arachyl ether, stearyl alcohol, a liquid oily ingredient, a moisturizing ingredient and water, and provides a medical dermatological preparation for external use, which reduces occurrence or degree of a side effect such as skin irritation in the medical dermatological preparation for external use. The present invention provides particularly a medical dermatological preparation for external use, which comprises adapalene and reduces occurrence and degree of a side effect such as skin irritation.