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DÉRIVÉ D'AMINOPYRAZINE ET MÉDICAMENT CORRESPONDANT
专利权人:
NIPPON SHINYAKU CO.; LTD.
发明人:
申请号:
EP10738621.1
公开号:
EP2394999B1
申请日:
2010.02.05
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
A compound represented by general formula [1] satisfying the following (I) or (II), or a pharmaceutical acceptable salt of the compound. (I) X is CH or N; R 1 is a halogen atom,; and R 2 is H, a halogen atom, CN, [2], [3], [8], [9], an -O-alkyl, an -0-(saturated ring), etc. [2]: -C(R C )(R D )(R E ) {R C to R E each are H, an alkyl, etc.} [3]: -N(R F )(R G ) {R F and R G each are H, OH, amino, a (hetero) aryl, etc.} [8]: -C(=O)R L {R L is an alkyl, OH, an alkoxy, amino, etc.} [9]: a (substituted)phenyl; (II) X is >;C-C(=0)R B {R B is a (substituted)amino, an alkoxy, OH, etc.}; R 1 is a halogen atom; R 2 is H; R 3 is H or OH; and R 3 and R 4 each are H or an alkyl.
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