Provided is a novel compound which has an effect of promoting insulin secretion from pancreatic ss cells and is useful as a prophylactic and/or therapeutic agent for diseases associated with high blood sugar, such as diabetes. A compound represented by general formula (1), a salt thereof, or a solvate of the compound or the salt. (In the formula, ring A represents a C6-C10 aryl group or a five- to ten-membered heterocyclic group Z represents O, N-R9, S(O)m, CH2 or C=O each of R1, R2, R3 and R4 is independently absent or represents a hydrogen atom, a halogen atom, a C1-6 alkyl group, a hydroxyl group, a nitro group, a tetrazolyl group or the like each of R5, R6 and R7 independently represents a hydrogen atom, a halogen atom, a cyano group or a carboxyl group R8 represents a C1-6 alkyl group, a C6-10 aryl group or the like each of R13 and R14 represents a hydrogen atom or a halogen atom and R15 represents a hydrogen atom, a hydroxyl group or an oxo group.)本發明係提供一種具有促進來自胰臟β細胞之胰島素分泌的作用,可用於作為因高血糖所引起之疾病、例如糖尿病的預防及/或治療劑的新穎化合物。本發明為一種化合物或其鹽或其等之溶媒合物,係由下述一般式(1)所示:[式中,A環表示C6-C10芳基或5-10員雜環基;Z表示O、N-R9、S(O)m、CH2或C=0;R1、R2、R3及R4彼此獨立為不存在或氫原子、鹵素原子、C1-6烷基、5-10員環雜-C1-6烷基、C1-6烷氧基、C3-8環烷基-C1-6烷氧基、C1-6烷基磺醯基、C1-6烷基磺醯氧基、C1-6烷基磺醯胺基、羥基、硝基、四唑基等:R5、R6及R7彼此獨立表示氫原子、鹵素原子、氰基或羧基;R8表示C1-6烷基、鹵C1-6烷基、C1-6烷氧基-C1-6烷基、C3-8環烷基、C6-10芳基、C6-10芳基-C1-6烷基、5-10員雜環-C1-6烷基等;R13或R14表示氫原子或鹵素原子;R15表示氫原子、羥基或側氧基]。
