NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
发明人:
BAGHDADI, Muhammad,SEINO Ken-ichiro
申请号:
EP16811690
公开号:
EP3311840A4
申请日:
2016.16.06
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
[problem] in order to provide a kind of reducing agent treatment-resistant resistance for treating cancer, treatment resistance can be removed or be reduced to the resistance reducing agent processing, in particular, drug resistant cancer and the therefore effect of raising treatment of cancer.Those contain as active constituent (group) treatment resistance reducing agent treatment-resistant cancer of the invention, and specific substance inhibits interleukin-34 to inhibit the expression of interleukin-34 in cancer cell to -1 protein receptor of colony-stimulating and/or substance. According to the present invention, the cancer of resistance, a kind of anti-treatment method, such as administration anticancer drug or radiotherapy are treated, it is possible to reduce, therefore, the effect for the treatment of of cancer, can be improved the side effect with occurrence risk can be suppressed.