INSTITUT CURIE;ABIVAX;UNIVERSITE DE MONTPELLIER;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
发明人:
TAZI, JAMAL,NAJMAN, ROMAIN,MAHUTEAU, FLORENCE,SCHERRER, DIDIER,CHEBLI, KARIM,HAHNE, MICHAEL
申请号:
CA2954951
公开号:
CA2954951A1
申请日:
2015.07.17
申请国别(地区):
CA
年份:
2016
代理人:
摘要:
The present invention relates to a compound of formula (I) wherein: Formula (II) means an aromatic ring wherein V is C or N and when V is N; Q is N or O, provided that R" does not exist when Q is O; R' independently represent a hydrogen atom or a group chosen among a (C1-C3)alkyl group, a halogen atom, a hydroxy! group, a - COOR1 group, a -NO2 group, a -NR1R2 group, a morpholinyl or a morpholino group, a N- methylpiperazinyl group, a (Ci-C3)fluoroalkyl group, a -O-P(=O)-(OR3XOR4) group, a (C1-C4)alkoxy group and a -CN group, and can further be a group chosen among:(IIa), (IIIa) or anyone of its pharmaceutically acceptable salt, for use in the treatment and/or prevention of an inflammatory disease.