JAN ERIC AHLFORS,KHALID MEKOUAR,NA (NOT APPLICABLE)
申请号：
IN8739/DELNP/2010
公开号：
IN2010DN08739A
申请日:
2010.12.08
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
The present invention relates to compounds of Formula I, IA, II, HA, III, or IHA and their pharmaceutical uses. Particular aspects of the invention relate to the use of those compounds for the selective inhibition of one or more caspases. Also described are methods where the compounds of Formula I, IA, II, IIA, III, or IIIA are used in the prevention and/or treatment of various diseases and conditions in subjects, including caspase-mediated diseases such as sepsis, myocardial infarction, ischemic stroke, spinal cord injury (SCI), traumatic brain injury (TBI) and neurodegenerative disease (e.g. multiple sclerosis (MS) and Alzheimers, Parkinsons, and Huntingtons diseases).
