SUN, Jeonghoon,TAM, Lei-ting Tony,HAN, HQ,KWAK, Keith Soo-Nyung,ZHOU, Xiaolan
申请号:
DK08742032
公开号:
DK2132314T3
申请日:
2008.03.06
申请国别(地区):
DK
年份:
2017
代理人:
摘要:
The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.