Jeonghoon Sun,Lei-Ting Tony Tam,Hui-Quan Han,Keith Soo-Nyung Kwak,Xiaolan Zhou,John Lu
申请号：
US13329897
公开号：
US08501678B2
申请日:
2011.12.19
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.
