SUN, JEONGHOON,TAM, LEI-TING TONY,HAN, HQ,KWAK, KEITH SOO-NYUNG,ZHOU, XIAOLAN
申请号:
PH12013502308
公开号:
PH12013502308A1
申请日:
2013.11.11
申请国别(地区):
PH
年份:
2015
代理人:
摘要:
The present invention provides variant activin IIB soluble receptor polypeptides and proteins capable of binding and inhibiting the activities of activin A, myostatin, or GDF-11. The present invention also provides polynucleotides, vectors and host cells capable of producing the variant polypeptides and proteins. Compositions and methods for treating muscle-wasting and other diseases and disorders are also provided.