The embodiment of the proposed invention relates an atropine prefilled syringe for aseptic administration of atropine. The drug atropine can support bacterial growth if it gets contaminated. The present syringe is prefilled and does not require filing the drug from ampoule and so there are no chances of atropine getting contaminated and hence avoids serious complications during surgery. Hence the present syringe enables aseptic administration of atropine. The ampoules are not required and hence the syringes are cost effective in terms of manufacture, handling, transport as well as disposal. In addition, medical wastage is also reduced as the ampoules are not at all required.