The embodiment of the proposed invention relates to Dexamethasone prefilled syringe which eliminates the risk of contamination and material loss. In Dexamethasone prefilled syringes chances of breakage and medical wastage are considerably reduced. The present syringes are prefilled with Dexamethasone and hence the drug are not exposed to the atmosphere prior to administration which prevents the drug from contamination. As the vials are not at all required, medical wastage considerably reduces. Also, it results in reduction of costs of vials thereby making the present invention economical.