Michael R. Hanley;Christopher J. Soares;Carolyn Marie Jodka;Qing Lin;David Geoffrey Parkes;Kathryn S. Prickett;Soumitra Ghosh;Christine Marie Mack;Diana Yvonne Lewis
发明人:
Christopher J. Soares,Michael R. Hanley,Diana Yvonne Lewis,David Geoffrey Parkes,Carolyn Marie Jodka,Kathryn S. Prickett,Soumitra Ghosh,Christine Marie Mack,Qing Lin
申请号:
US13364250
公开号:
US20120196796A1
申请日:
2012.02.01
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to novel compounds having a function of a peptide in the amylin family, related nucleic acids, expression constructs, host cells, and processes production of the compounds. The compounds of the invention include one or more amino acid sequence modifications. In addition, methods and compositions are disclosed to treat and prevent metabolic disorders such as obesity, diabetes, and increased cardiovascular risk.