Amylin family polypeptide-6 (AFP-6) analogs and methods of making and using them

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专利权人:

发明人:

申请号：

EP12186128.0

公开号：

EP2631244A1

申请日:

2005.10.11

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention relates to Amylin Family Polypeptide-6 (AFP-6) analogs, which include derivatives and fragments, related nucleic acids, expression constructs, host cells, and processes for recombinant production of the AFP-6 analogs.The AFP-6 analogs of the invention include one or more amino acid sequence modifications. In addition, methods and compositions are disclosed to treat and prevent conditions such as metabolic and cardiovascular disorders, e.g., obesity, diabetes, metabolic syndrome, myocardial ischemia, and increased cardiovascular risk.

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