Michael R. Hanley;Christopher J. Soares;Carolyn M. Jodka;Soumitra S. Ghosh;Qing Lin;Diana Y. Lewis;David Geoffrey Parkes;Kathryn S. Prickett;Christine Marie Mack
发明人:
Christopher J. Soares,Michael R. Hanley,Diana Y. Lewis,David Geoffrey Parkes,Carolyn M. Jodka,Kathryn S. Prickett,Soumitra S. Ghosh,Christine Marie Mack,Qing Lin
申请号:
US10589054
公开号:
US08114958B2
申请日:
2005.02.11
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to obesity related polypeptides (ORPs), related nucleic acids, expression constructs, host cells, and processes production of the obesity related polypeptides. The ORPs of the invention include one or more amino acid sequence modifications. In addition, methods and compositions are disclosed to treat and prevent metabolic disorders such as obesity, diabetes, and increased cardiovascular risk.