PROBLEM TO BE SOLVED: To provide a suppository which excels in quick solubility (decay properties) in addition to resting properties and storability and has a high therapeutic effect.SOLUTION: The suppository comprises (A) a fatty acid triglyceride which is solid at normal temperatures, (B) one or two or more glycerin fatty acid esters having 14-18C which are solid at normal temperatures, (C) a base component sustained in the lower rectum, (D) an ester oil which is a clear liquid at normal temperatures and (E) a soybean lecithin.COPYRIGHT: (C)2009,JPO&INPIT【課題】静止性、保管性が優れる他、速溶性(崩壊性)にも優れ、治療効果の高い坐剤を提供すること。【解決手段】 次の成分(A)~(E)(A)常温で固体の脂肪酸トリグリセリド、(B)常温で固体の炭素原子数14から18のグリセリン脂肪酸エステルの1種または2種以上、(C)直腸下部滞留性基剤成分、(D)常温で澄明な液体のエステル油、(E)大豆レシチン、を含有することを特徴とする坐剤。【選択図】図1
