Gary Shapiro,Kevin Brower,Patrick Finn,Richard C. Gregory,Rao Koduri,Feng Liu,Natalia Malkova,Parminder Mankoo,Jack R. Pollard,Huawei Qiu,Joachim Theilhaber,Christopher Winter,Marcella Yu
申请号:
US15875532
公开号:
US20180244763A1
申请日:
2018.01.19
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention provides an improved pan-TGF-β antibody for treatment of conditions that are mediated by TGF-β, including autoimmune diseases, fibrotic conditions, and cancers. Also provided are methods and uses of the antibody in conjunction with other immunomodulatory agents such as an anti-PD-1 antibody.