Shapiro, Gary,Brower, Kevin,Finn, Patrick,Gregory, Richard C.,Koduri, Rao,Liu, Feng,Malkova, Natalia,Mankoo, Parminder,Pollard, Jack R.,Qiu, Huawei,Theilhaber, Joachim,Winter, Christopher,Yu, Marcel
申请号:
AU2018209391
公开号:
AU2018209391A1
申请日:
2018.01.19
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
The invention provides an improved pan-TGF-β antibody for treatment of conditions that are mediated by TGF-β, including autoimmune diseases, fibrotic conditions, and cancers. Also provided are methods and uses of the antibody in conjunction with other immunomodulatory agents such as an anti-PD-1 antibody.