Robert Hilgraf;Ronald J. Albers;Veronique Plantevin-Krenitsky;Leticia Ayala;Kevin Hughes;Sayee G. Hegde;Lisa Nadolny;Maria Mercedes Delgado Mederos;Meg McCarrick;Moorthy S.;Steven S. Clareen;Adam Kois
发明人:
Ronald J. Albers,Leticia Ayala,Steven S. Clareen,Maria Mercedes Delgado Mederos,Robert Hilgraf,Sayee G. Hegde,Kevin Hughes,Adam Kois,Veronique Plantevin-Krenitsky,Meg McCarrick,Lisa Nadolny,Moorthy S.
申请号：
US12404413
公开号：
US08101588B2
申请日:
2009.03.16
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Provided herein are Aminopurine Compounds having the following structure:wherein R1, R2 and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.
