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Methods of modulating inflammatory cell recruitment and gene expression using haloaryl substituted aminopurines
专利权人:
Brian Edwin Cathers;Brydon L. Bennett;Kate Northcote
发明人:
Brydon L. Bennett,Kate Northcote,Brian Edwin Cathers
申请号:
US12779083
公开号:
US08440661B2
申请日:
2010.05.13
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Provided herein are Aminopurine Compounds having the following structure:wherein R1, R2 and R3 are as defined herein, compositions comprising an effective amount of an Aminopurine Compound and methods for treating or preventing cancer, a cardiovascular disease, a renal disease, an autoimmune condition, an inflammatory condition, macular degeneration, ischemia-reperfusion injury, pain and related syndromes, disease-related wasting, an asbestos-related condition, pulmonary hypertension or a condition treatable or preventable by inhibition of the JNK pathway comprising administering an effective amount of an Aminopurine Compound to a patient in need thereof.
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